COGS 11 Lecture Notes - Lecture 4: Substantia Nigra, Striatum, Nigrostriatal Pathway

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10 Nov 2018
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If you give your brain the opportunity to get addicted, it will. False sense of confidence: got it from prescription means it"s okay (not) After a certain time, the dose response curve shifts. Anything that moves the body out of homeostasis is a stresser. Anything that produces dopamine can be addictive. The dopamine brings your body to a high -> your body will predict that you"ll take your drug at a certain time -> if you don"t get it, then your body will be at a low . Preference task- same environment, same time, etc can. Drug effect decreases with increased exposure produce triggers. The withdrawal effect is proportional to your tolerance to the drug. Coming off the drug can be a big stresser -> need to be careful when coming off the drug. Drug exposure leads to the development of adaptive neural changes that produce tolerance by counteracting the drug effect. Alerting the function of neurotransmitters can change behavior.

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