ANFS140 Lecture Notes - Lecture 6: Type Iv Collagen, Connective Tissue, Mesenchymal Stem Cell
3 Apr 2017
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Structure of basement membrane: has several components. Composites much stronger and resist stress/strain than single material. Glycoprotein long chains of sugars; attached to protein core (makes proteoglycan) These structures are synthesized by epithelial cells. Can"t attach unless basement membrane is made. Several connective tissue types: fibrous connective tissue, cartilage, bone, fat. These are connective tissues bc they come from mesenchymal stem cells undifferentiated stem cell. Most found surrounding small blood vessels (capillaries) Differentiation is triggered by diff factors and hormones. 4-sulfate chondroitin (6-sulfates) keratin heparin anti-coaggulant: protein core + gags, the gags are negatively charged, types of fibrous connective tissue: loose. H"s of h2o attach electrostatically to the gags. Movement to inflamed areas trapping substances killing cells antiparasitic and bactericidal activity participating in immediate allergic reactions. Lymphocytes-- a form of small leukocyte (white blood cell) with a single round nucleus, occurring especially in the lymphatic system. Cartilage: stem cell is the mesenchymal stem cell.
