BISC401 Lecture Notes - Lecture 20: Protein Kinase, Cyclic Adenosine Monophosphate, Lysine

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Resident er proteins: cargo taken back into the er from the gn because some of these proteins which are. Endocytic pathway for internalizing low-density lipoprotein (ldl: ph dictates when interactions will take place, and when they are released. Signaling over short and long distances: autocrine target sites on same cell; example characteristic of tumor cells, endocrine long distance, distant target cells; usually through the blood stream; example. Diversity of membrane receptors: receptors can be localized on the membrane, receptors can also be intracellular, such as those in the nuclear receptor family, 4 types. Signaling by cell surface receptors: first messenger, rapid, short term effects, modification of cellular metabolism, function, movement, second messengers, slow, long term effects, modification of gene expression, development. Properties of first messengers: signal can be, physical light, touch, heat, chemical small molecules, gases, peptides, soluble proteins, membrane proteins. Structure of second messengers: calcium ion, camp, cgmp, dag, ip3.

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