CHEM214 Lecture Notes - Lecture 2: Cysteine, Isoleucine, Valine
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14 Mar 2018
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Related Questions
Consider the peptide:
NH2-GAPAGPAGTGKTETTKDLAKSMALLCWFNCS-COOH
Table I. pK values of some amino acids
amino acid | pK of side chain or terminal group |
---|---|
Alanine (Ala or A) | uncharged |
Arginine (Arg or R) | 12.5 |
Asparagine (Asn or N) | uncharged |
Aspartic acid (Asp or D) | 3.9 |
Cysteine (Cys or C) | 8.3 |
Glutamic acid (Glu or E) | 4.3 |
Glycine (Gly or G) | uncharged |
Histidine (His or H) | 6.0 |
Leucine (Leu or L) | uncharged |
Lysine (Lys or K) | 10.8 |
Phenylalanine (Phe or F) | uncharged |
Serine (Ser or S) | uncharged |
Tryptophan (Trp or W) | uncharged |
Tyrosine (Tyr or Y) | 10.9 |
Valine (Val or V) | uncharged |
peptide N terminus | 7.8 |
peptide C terminus | 3.6 |
Using Table I above, determine the net charge of the peptide at pH9.
(the answer is not -1 or 1)