KAAP221 Lecture Notes - Lecture 19: Hepatic Artery Proper, Enteroendocrine Cell, Osmosis

• School: University of Delaware
• Department: Kinesiology & Appl Physiology
• Course: KAAP221
• Professor: Shannon Lennon

Document Summary

Active stem cells at base of each pit replace superficial cells shed into chyme. Each pit communicates with several gastric glands: gastric pits, cells of gastric glands. Submucosa: muscular layer - oblique, circular, longitudinal, gastric glands. Predominantly in the fundus and body - secrete most of acid and enzymes for gastric digestion; parietal cells and chief cells are main ones; secrete 1. 5l gastric juice per day. Glands in pylorus - secrete mucus and hormones that coordinate and control digestive activity. Produce intrinsic factor - aids in vitamin b12 absorption; if b12 is not bound to intrinsic factor, it will not be absorbed. Produces hcl - activates pepsinogen; keep ph at 1. 5-2. Chief cells - pepsinogen is activated by hcl to become pepsin, which digests proteins. Parietal cells do not create hcl in cytoplasm. H+ generated as carbonic anhydrase converts co2 and h2o to carbonic acid. Co2 + h2o > h2co3 > hco3- + h+