NSCI320 Lecture Notes - Lecture 1: Axon Hillock, Axon Terminal, Neurite
7 Mar 2017
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Document Summary
Cajal and golgi: golgi, golgi-stain showed two parts of the neuron (soma = soma and perikaryon and neurite. Believed in neuronal doctrine (neurons adhere to cell theory). Neuronal doctrine: neurons adhere to the cell theory. The neuronal membrane at rest (chapter 3: chemicals in cytosol and extracellular fluid (importance of water), ionization, water uneven charge, ions spheres of hydration. Neuronal membrane (channel proteins, pumps: hydrophilic and hydrophobic, lipids = hydrophobic, contribute to resting and action potentials, phospholipid bilayer, channel proteins, r groups and nonpolar r groups, ion selectivity and gating, pumps. Ohm"s law: diffusion, i = v/r, used for the electrical current flow across a membrane. Goldman equation: derived from the nernst equation, takes into account the permeability of the membrane to different ions. The action potential (na+ k+ ca++ release of neurotransmitter) Ii: must cross for action potential to occur all-or-none rule, caused by influx of na, has both diffusion and electrostatic pressure.
