NURS312 Lecture Notes - Lecture 4: Common Bile Duct, Pancreatic Duct, Bile Duct

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Ast - aspartate aminotransferase; intracelular enzyme involved in aa metabolism; in large concentrations in liver, skeletal muscle, heart, brain, and rbc"s; released into blood when tissue, especially liver, is damaged (was sgot) Alt - alanine aminotransferase; intracellular enzyme involved in aa metabolism; in large concentration in liver; released with tissue damage (was sgpt) Bound to albumin and transported in blood to liver where metabolized. A&e - oral-fecal route, sex, household contamination, salad bar, bottom feeding seafood, undercooked seafood. C, b, d - blood and sexual transmission. Chronic persistent - benign; few symptoms but you feel like crap; minimal necrosis. Chronic active - progressive liver destruction with cirrhosis, chronic liver failure and can go into death: cirrhosis of the liver, highly associated with alcohol ingestion, definition and pathophysiology. Hepatic scarring caused by inflammation in the liver; produces ischemia which kills out sections of the liver and alters function.

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