NURS312 Lecture Notes - Lecture 2: Mean Corpuscular Volume, Polycythemia Vera, Fetal Hemoglobin
9 Oct 2018
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Polycythemia vera - primary; don"t see this as much as secondary. Increased blood volume; increased viscosity; increased hematocrit very high risk for stroke or embolism: antigens on rbc surface, abo - igm antigen markers. Code for a, b, or neither (o: o - no antenna, no markers, can give blood to anyone; but these do make anti-a and. Anti-b antibodies: one allele from each parent - ab are co-dominant; universal recipients = ab, universal donor = o. Can be internal or external - the loss of blood can drop their bp or put them in shock: decreased production (i. e. , aplastic anemia) Problem with bone marrow - it"s not making enough rbc"s. Can be decreased reticulocytes - not maturing fast enough. Can be a kidney issue - decreased kidney function means not producing enough erythropoietin. Can be decreased components of hgb because of poor nutrition - i. e. iron deficiency anemia or pernicious anemia (malabsorption of b12: increased destruction (hemolysis)
