BSC 2010 Lecture Notes - Lecture 4: Dna Replication, Cytokinesis, G1 Phase

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Divide cytoplasm and separate into two new cells. 3 domains of the living world: bacteria - prokaryotes, archaea - prokaryotes, eukarya - eukaryotes, prokaryotes - foundation for life. Eukaryotes have many chromosomes instead of just one circular chromosome. Eukaryotic cells divide by mitosis followed by cytokinesis. One nucleus produces two daughter nuclei, each containing the same number of chromosomes as the parent nucleus. G1 (gap 1) - hanging out, may last a long time. The chromosomes become much more tightly coiled and condensed. Each chromosome has two dna molecules called sister chromatids, joined at a region called the centromere. Centrosomes served as poles toward which the chromosomes move. The spindle forms between the poles from microtubules. Kinetochore microtubules attach to kinetochores on the chromatid. Sister chromatids attach to kinetochore microtubules from opposite sides so that the two chromatids will move to opposite poles. The nuclear envelope breaks down and chromatids attach to the kinetochore microtubules.

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