Ch. 11: Gene Expression

2 Pages

Biology - Biological Sciences
Course Code
BSC 2010
Gerlach, Nicole

This preview shows 80% of the first page. Sign up to view the full 2 pages of the document.
3/13/13 Ch. 11 I. Gene Expression A. Gene expression – final production of a functional gene product (e.g. protein) B. Gene regulation – control over timing and rate of gene expression C. Genomic totipotency – all somatic cells share the same DNA D. House-keeping genes – genes that are so critical to day-to-day existence that they are always “on” 1. Constituitve expression – genes that are always “on” E. Luxury genes – those that are only by specific cells and/or at specific times 1. Inducible expression – expressed only when protein is needed by cell F. Gene expression can be regulated at any point in central dogma G. Prokaryote gene regulation – few regulatory controls for multiple structural (protein- coding) genes H. Eukaryotic gene regulation – multiple regulatory controls for each structural gene II. Positive and Negative Regulation A. Transcription factors (regulator proteins) – control when a gene is active B. Negative regulators – gene is constituitively repressed by repressors C. Positive regulators – gene is not typically expressed but can be induced by an activator D. Operons (in bacteria) – what gene expression is based on 1. Contains operator – short stretch of DNA near the promoter that controls transcription E. Lac operon – specific chromosomal region of E. coli chromosome that contains genes needed for the catabolism of lactose 1. Repressor constituitiveley expressed; operon is not expressed III. Eukaryotic Gene Expression A. Gene regulation is more complex (e.g. specialization) 1. Gene regulation is required over both space (cell-to-cell) and time (zygote to multicellular adult) B. Larger genomes C. More complicated cells (with mitochondria, nuclear membranes) D. Prokaryotes: operons; multiple structural genes under a single regulatory control E. Eukaryotes: operons rare; multiple regulatory controls for single structural genes F. C
More Less
Unlock Document

Only 80% of the first page are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.