HSC 3102 Lecture Notes - Lecture 10: Ovarian Cancer, Endometrial Cancer, Colorectal Cancer
Document Summary
Can be caused by tobacco, radiation, uv rays from sun. Affects these three genes: proto-oncogenes involve in normal cell growth and division, tumor suppressor genes also involved in growth and division, dna repair genes fixing damaged dna. Metastic cancer spreads from place where it first started to other parts of body. Hyperplasia cells within a tissue divide faster than normal and extra cells build up. Dysplasia buildup of extra cells, that are abnormal. Carcinoma most common, formed by epithelial cells: adenocarcinoma produce fluid or mucus, basal cell begins in basal layer of epidermis, squamous cell forms in squamous cells, transitional. Sarcoma form in bone and soft tissues. Leukemia begins in lymphocytes b or t cells, abnormal lymphocytes build up in lymph nodes and vessels. Multiple myeloma begins in plasma cells. Melanoma begins in cells that become melanocytes. Lung cancer accounts for about 14% of all cases but 28% deaths.