ADSC 3300 Lecture Notes - Lecture 11: Phosphoenolpyruvate Carboxykinase, Anaerobic Glycolysis, Glycerol
14 Apr 2017
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Glucose + 2 adp + 2 nad 2 pyruvate + 2 atp + 2 nadh. ***difference aerobic and anaerobic glycolysis is the energy it takes to convert pyruvate to lactose. Bacteria doesn"t have mitochondria, so the rumen microbes do not have oxidative phosphorylation. But they can"t breakdown further to acetyl coa: unsaturated fats go to saturated fats (biohydrogenation, methane and hydrogen are both greenhouse gasses (these aren"t good) Formic gas going to methane is a way to get rid of hydrogens: acetate goes to eventually to make milk fat, propionate goes to make lactose (disaccharide) A high grain diet tends to result in higher propionate. Gluconeogenesis: precursors include: carbon sources for pyruvate. Lactate, most amino acids, propionate, and glycerol: 1st step: pyruvate kinase catalyzes pep to pyruvate (adp atp aka gain 1. Delta g is very negative, so it"s an irreversible step. Two enzymes that get around that step is: Biotin; pyruvate carboxylase is a biotin dependent enzyme.
