GENE 3200 Lecture Notes - Lecture 2: Chromosomal Inversion, Chromosomal Translocation, Telomere

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28 Apr 2019
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Meiosis with paracentric inversion: results in inversion loops, get very stereotypical chromosome loops. One is fine and the other one isn"t: 2 chromatids and 2 homologous chromosomes. If you get crossing over event at a, you don"t expect any trouble during crossing over. If crossing over occurs outside of f and g, there"s no affect but if there"s crossing over problem inside inversion loop, then you will have problems: start from inside of drawing and work out. Start with #3, then 4, 2, and 1: then you must do a cross over inside the loop. When you do this, just follow the lines. You know crossover will be b/w two 2 will be parental and 2 will be recombinants. Affect of inversion heterozygote = reduced fertility* (half gametes are nonfunctional because they lack information and other half are functional because they have all information) **

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