POUL 3000 Lecture Notes - Lecture 2: Sinusitis, Antigen, Antigen Presentation

• School: University of Georgia
• Department: Poultry Science
• Course: POUL 3000
• Professor: Benson

Document Summary

Heterophils: major phagocytic leukocyte, tend to be increased during bacterial infections, how do neutrophils/heterophils kill, respiratory burst (release of superoxide anion, suicide bomber (good, contain an enzyme (nadph. Oxidase) that will reduce oxygen to create free radical (superoxide anion: o2 to o2, sod (superoxide dismutase that generates h2o2, myeloperoxidase which generates hclo (hypochlorite) It"s like bleach will be toxic and will kill all cells that surrounds it: disadvantage: causes tissue damage, phagocytosis (increased activity by priming with il-2 and opsonization, primed by opsonization, antibiotics and complement proteins do this. In tissues: kupffer cells, alveolar macrophages (a bird lacks these which are in the lungs), microglia, osteoblast. Ige also has an essential role in type i hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, & specific types of chronic urticaria and atopic dermatitis.