BIOS 222 Lecture Notes - Lecture 11: Mecha, Reduction Potential, Pyruvic Acid

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silverwildebeest198

31 May 2016

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Fewer protons in matrix space and more protons outside mitochondria. Final electron acceptor is oxygen h2o contributes to strength of proton gradient. Tca cycle-remove co2 molecules from the intermediates: citrate and applicated gluterate. Slide on electron transport chain- there are 2 electrons that nadh carries and are donated to the first component of the etc. Then, the last receiving molecule in the etc is cytochrome c oxidase which donates electrons to o2 to make water. During these steps while electrons are being transferred, protons are being carried from matrix side of membrane to innermembrane space, making the proton gradient. Etc is the sequence of steps in which intermediates become better electron acceptors and poorer e donors. Electron transport slide- each step better electron accept than prev. Slide on an e- chemical grad as we"re creating ec grad across mitochond memb. Pumping protons to gen it, and being consumed to become water.

Related Questions

1. Compared to the generation of ATP by oxidative phosphorylation, what is a major difference in mechanism of ATP generation by substrate-level phosphorylation in glycolysis?

A. A proton gradient is not involved

B. The ATP produced has less energy content because oxygen was not involved.

C. Substrate level phosphorylation occurs in the inter-mitochondrial space

D. One can't generalize without knowing the substrate.

2. Which of the following statements is true?

A. Because the electrons in NADH are at a higher energy than the electrons in reduced ubiquinone, the NADH dehydrogenase complex can pump more protons than can the cytochrome b-c1 complex.

B.The pH in the mitochondrial matrix is higher than the pH in the intermembrane space.

C. The proton concentration gradient and the membrane potential across the inner mitochondrial membrane tend to work against each other in driving protons from the intermembrane space into the matrix.

D. The difference in proton concentration across the inner mitochondrial membrane has a much larger effect than the membrane potential on the total proton-motive force.

use the following words: protons, NADH, electron gradient, ADP, FADH2, ATP, ATPsynthase, water, proton gradient, electrons

A molecule generated in both glycolysis and Krebs cycle, called ____________ , donates ____________ to the first protein in the electron transport chain.

At the same time, a molecule generated only in the Krebs cycle, called ____________ , donates ____________ to the second protein in the electron transport chain.

As the ____________ move through the transport chain, ____________ move through membrane proteins from the matrix to the intermembrane compartment.

At the end of the electron transport chain, ____________ bind to oxygen, forming ____________ .

The electron transport chain creates a(n) ____________ , which dissipates through an enzyme called ____________ .

As ____________ move through this enzyme, phosphate is added to ____________ , forming ____________ .

Each protein in the electron transport chain moves electrons from one carrier to another, what are the two carriers on either side of each protein? What are the cofactors of each protein? Which proteins can pump protons. Where does cytochrome C carry electrons from and to? Quinone? Which protein is a direct tie to the citric acid cycle? Where does the Q cycle occur? How many molecules of ATP are formed per NADH? How do you know?

BIOS 222 Lecture Notes - Lecture 11: Mecha, Reduction Potential, Pyruvic Acid

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