BIOS 286 Lecture Notes - Lecture 5: Nmda Receptor, Synaptic Plasticity, Limonene
Document Summary
Lateral inhibition enhances contrast and makes mitral cells more selective than. Primary mitral dendrite enters only one glomerulus. Mitral cells do not interact with each other directly. Overlapping but distinct bulb patterns in response to two similar but distinct odorants. Clearly this has nothing to do with sensitivity. Each pyramidal cell has 5,000 synapses with different mitral cells. Each mitral cell could project to as many as 1/10 of the pcells. Each pcell could be connected to 1/10 of the mitral cells. Olfactory cortex has cells that can respond to unique combinations of odor fragments. Synapses in olfactory cortex and other cortical areas, including neocortex and hippocampus exhibit plasticity. Plasticity: the ability to be functionally modified by their own activity. Most important form of synaptic plasticity is long-term. Ltp is a long-lasting increase in the potency of synaptic transmission that can occur at excitatory synapses. Postsynaptic spine has ampa-type and nmda-type glutamate receptors.
