KN 252 Lecture 3: Components of the Blood – Plasma and Formed Elements

5 Pages

Course Code
KN 252
Marone Jane, Michael Jones

This preview shows pages 1 and half of page 2. Sign up to view the full 5 pages of the document.
Components of the Blood – Plasma and Formed Elements Blood Functions • Transportation/Distribution – of substances • Maintenance of Homeostasis – temperature regulation; chemical buffering/ clotting mechanisms to maintain normal general function • Protection – immunity Plasma – pale yellow fluid Three components: • Proteins and Lipids – albumin, globulins, fibrinogen (clotting proteins) • Dissolved Components – ions, gases, glucose • Serum – no clotting proteins (it’s just plasma with all components except for the clotting proteins) Plasma Maintenance (two parts): • Fluid Maintenance (to maintain volume) – consumed and removed (input = output) • Maintenance of Solutes – liver, kidney, intestine, endocrine gland, immune tissues Hormonal Control The kidney secretes erythropoietin (hormone that stimulates stem cell) § The kidney is very sensitive to low levels of O2 in the blood § When O2 in blood drops, the kidney release more erythropoietin so that more RBC’s will be produced ERYTHROCYTES (RBC) Structure Function Production Disorders **Not true cells Transport O 2rom the Erythropoiesis: Anemias: few RBC’s; decrease lungs to tissues process of RBC hemoglobin content; abnormal production hemoglobin Cell membrane Transport CO f2om Embryo, fetus: Polycythemia: excess numbers surrounding protein the tissues to the lungs occurs in multiple of RBC’s network tissues Cytoplasm w/ lipids, Hemoglobin: Hb After birth: occurs in ATP, carbonic carries O2on Fe; on bone marrow and anhydrase, hemoglobin CO 2 lymph tissue (coloring) No nuclei, no Adulthood: occurs mitochondria/ribosomes bone marrow at certain regions Erythropoiesis is a 15 day process in bone marrow; within bone marrow reside stem cells (hemocytoblasts – PM contain receptors for different types of hormones), so the hormonal stimulation will determine the commitment of that cell / pathway of development in which that cell will go. Once erythropoietin hormone binds to stem cell, the hemocytoblast will become a proerythroblast (committed cell); then the committed cell will differentiate into different phases of development à phase 1 = synthesis of ribosomes (at this point it is a true cell b/c it still has nucleus/ribosomes) à phase 2 = accumulation of hemoglob
More Less
Unlock Document

Only pages 1 and half of page 2 are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.