NURS 210 Lecture Notes - Lecture 1: Teratology, Creatinine, Organogenesis
Document Summary
Formulation of drugs into dosage forms suited for delivery to the site of action. Drug dosage forms determine how quickly the drug disintegrates or dissolves and is absorbed. A drug is made up of one or more active ingredients and various additives. Examples of active ingredients: alkaloids, glycosides, polypeptides, salts, steroids. Examples of additives: binders, diluents, disintegrators, dyes, flavorings, fillers, lubricants, vehicles. Drugs are formulated and administered to produce either local or systemic effects; may be solid (e. g. , tablets, capsules, patches); semisolid (e. g. , ointments, creams, suppositories); or liquid (e. g. , elixirs, suspensions, syrups) In order for a drug to exert its effect on a particular tissue, it has to get to that site and in sufficient quantity. In therapeutics, the idea is to achieve and maintain a certain concentration of drug within the body. The four processes that need to be considered in achieving and maintaining this goal are.