BIO 152 Lecture Notes - Lecture 9: Neurotrophic Factors, Cell Adhesion, Autocrine Signalling
Document Summary
Responding cell: has receptor proteins that bind to the signaling molecule. Signaling and responding cell are far apart and signal travels through bulk flow: paracrine. Within short distance, usually just a few cells from signaling to responding cell: autocrine. Feedback to the cell to make sure it is sending the right amount of signal and that the signal is working: juxtacrine. When signaling molecule is attached to signaling cell. Way of cellular adhesion, two cells can differentiate. Maintenance of consistent internal environment: set point, within a range of tolerance. Dynamic regulation: change can take time: lag. Effector: part that actually changes the body environment, makes the body different. Negative feedback: maintain homeostasis, example: red blood cells, maintains a set point, takes some input, compares it set point, if it is too high or low it raises or lower the environment, constant cycle.