MCDB 310 Lecture Notes - Lecture 21: Q Cycle, Cytochrome, Cytochrome C Oxidase

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Overview of oxidative phosphorylation and photophosphorylation: these two processes produce most atp for most biological reactions for many organisms. Oxidative phosphorylation: catabolism of carbs, lipid, amino acids converge on cellular respiration reductive pathways provide electrons via nadph and fadh2, occurs in mitochondria. Photophosphorylation: process where sunlight is captured and used to drive atp synthesis, 100% needs light. Involves oxidation of h2o to o2: nadp+ is the final electron acceptor, occurs in chloroplasts. Universal electron carriers: oxidative phosphorylation starts with electron transfers, dehydrogenases collect electrons from catabolic pathways and transfer them to, nicotinamide nucleotides - nad+ and nadp+ Nad+ and nadp+ do not cross the inner mitochondrial membrane: flavin nucleotide - fad and fmn, electron transferring flavoprotein, ubiquinone (coenzyme q, lipid soluble. Long isoprenoid side chain: stays in lipid, very mobile, shuttles electrons from different carriers, accepts one electron (and 1 h+) - semiquinone, or two electrons - ubiquinone.

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