MCDB 310 Lecture Notes - Lecture 11: Guanylyl Cyclase, Signal Transduction, Adrenergic Receptor
Document Summary
Learning goals: to identify examples of the four basic receptor types, to understand the six major features of signal transduction pathways, to identify molecules involved in example signal transduction pathway. Starting at the plasma membrane, there is a signal transduction pathway that ultimately leads to the activation of some kinds of cellular response. There is a signaling molecule that interacts with the receptor and then relay molecules in a signal transduction pathway undergo many binding events and chemical changes leading to the activation of a cellular response. Vision is due to opsins that can detect photons and turn them into a signal in a signaling transduction pathway. Odorants: bind to membrane proteins called gpcrs (g protein coupled receptors) and transduce signals. Gate ion channels: ligand is the signal, target top steps in signaling cascades. G-protein coupled receptors (gpcrs: some of the hormone receptors (beta-adrenergic, target top steps in the signaling cascades.