MCDB 427 Lecture Notes - Lecture 16: Point Mutation, Antibody, Western Blot

• School: U of M
• Department: Molecular, Cellular and Developmental Biology
• Course: MCDB 427
• Professor: Janine Maddock

Document Summary

Slide 1 complicated that it would take too long to cover. So some of the stuff she will skip. So if you take away the cap, the rna will be degraded easily in the cytoplasm. This is a chapter that has either no data or when it gets into the data, it"s so. Whether you polyadenylate and (cid:887)" cap the mrna will determine if it is stable or not. You don"t need as quick of a response if your doubling time is longer. Looking at any given rna, the rna may live only from 2 to 10 mins. So any individual rna might be short or long lived. It has to do with the polya tail or the cap: stability of casein, stability of transfurin receptor, sirnas. Stability is equilivant to half life which tells us how long an rna sticks around.