PSYCH 230 Lecture Notes - Lecture 8: Electrodermal Activity, Chemical Synapse, Raised Floor
Document Summary
Pre-synaptic facilitation: neuron 3 hyperpolarization neuron 1 (ipsp) Increase amount of nt released: lowers floor. Neurotransmitters: dozens- but only 5-10 major types, generalizations, anatomical localization, effect (epsp or ipsp, ligands bind to receptors, neurotransmitters (locks, drugs. Catecholamines: very similar, usually cause ipsp by itself, can have complex effects and change role if it is being co-released with other nts. Norepinephrine: sympathetic autonomic system (other half of autonomic ns) Serotonin: more distantly related to catecholamines, famous in depression, heavily produced in raphe nucleus (cid:894)i(cid:374) (cid:271)rai(cid:374) ste(cid:373)(cid:895); (cid:862)sea(cid:373)(cid:863, mixed epsps and ipsps depending on neurons. Glutamate: epsps, cortex, and in rest of brain, excitatory. Gaba: gamma amino butyric acid, cortex, and rest of brain. Endorphin and enkephalin: natural, pain (analgesia effects) and reward, complicated neuronal effects, mixed epsps and ipsps, many are generated in the brainstem, periaqueductal gray (pag) area. If excitatory, will inhibit (and vice versa: prevent release - presynaptic, block receptors postsynaptic.
