BIOL 100 Lecture Notes - Lecture 39: Tobacco Mosaic Virus, Oseltamivir, Intracellular Parasite
23 May 2016
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They took the diseased tobacco plant, grind it up, and run it through a fine filter that even removes bacteria. They then took the extract and exposed a healthy plant to it. This plant becomes diseased: in 1898, another individual does the same experiment but they run the extract through an agar gel. They expose healthy plants to the extract and the plants become diseased. They realized it"s something smaller than a bacteria and named it the contagium vivum fluidum and they later shorten this to virus . They then crystallized the virus and looked at it"s structure. They see that the structure is very different from bacteria. They also recognized that if you rehydrate the crystals, they can re-infect a plant to cause the disease. Viroid: the simplest infectious agent- it is one virus, its dna (genetic material), and it"s protein capsin. They require a living host cell in order to replicate.
