ANIMLSCI 332 Lecture Notes - Aorta, Calcification, Milk Fever
Document Summary
Works in concert with pth to increase blood calcium levels by promoting the resorption of ca from the renal tubule and by the resorption of ca from bone stores. Increases the enteric absorption of calcium through increased synthesis of calcium. Binding protein and through an unspecified nongenomic process. Increases enteric phosphate absorption also with some unknown mechanism process appears to be independent of calcium concentration. Plays a critical role in the formation bone formation (mineralization) as well as mobilization (demineralization) of bone calcium homeostasis) Mineralization thought to be mediated through 1,25 dihydroxy vit d via the osteoblasts. Other vit d metabolites may be involved in this process (24,25 dihydroxy vit d). Homeostasis) 1,25 dihydroxy vit d affects the osteoclasts through the differentiation of macrophages. Osteoporosis: loss of bone mass starting in the third to forth decade in females and forth to fifth decade in males.