BIOCHEM 523 Lecture Notes - Lecture 9: Reaction Rate Constant, Oxyanion Hole, Carboxypeptidase
31 Oct 2017
School
Department
Course
Professor
Document Summary
There are six major classes of enzymes: oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases. Transferases catalyze transfer of functional groups from one molecule to another. For a hypothetical zeroth order reaction, v would be independent of concentration, so v = k, and [a]t = [a]o - kt v = -d[a]/dt = k[a], and [a]t = [a]e^-kt. 2a b, v = k[a]^2, and 1/[a]t = 1/[a]o + 2kt. For more complicated reactions, the integrated expressions become more complicated, Note that the units of the rate constant, k, change with the order of the reaction but determining the order of the reaction is simple. Simple 2nd order, 2a b, v = k[a]^2. 2nd order with two reactants, a + b c, 3rd order with two reactants, 2a + b c, Catalyzed and uncatalyzed reactions high-energy transition state to form products. This free energy barrier is called the activation energy.
