BIOCHEM 523 Lecture Notes - Lecture 21: Phosphoglycerate Kinase, Light-Independent Reactions, 3-Phosphoglyceric Acid

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Biochem423/523 - lecture 21 - the calvin cycle & alternative pathways. The calvin cycle uses the atp and nadph generated in the light reactions to fix. The calvin cycle has two stages atmospheric co2 into carbohydrate. First, co2 is fixed by addition to ribulose-1,5-bisphosphate (rubp) and hexoses. Carbon dioxide is incorporated into glyceraldehyde-3-phosphate (gap) through the. The acceptor for co2 is ribulose-1,5-bisphosphate (rubp), where co2 from the air. This reaction is catalyzed by ribulose-1,5-bisphosphate carboxylase (rubisco) The rubisco enzyme is first activated by carbamation of an active site lysine residue e-amino group of lysine, is analogous to the carbamates on the n-termini of hemoglobin. Form i of rubisco is the most important of the four varying forms. This carbamate, formed by nonenzymatic reaction of nonsubstrate co2 with the. The two 1,3-bisphosphoglycerates so produces are then reduced to two. Glyceraldehyde-3-phosphate dehydrogenase catalyzed the oxidation of nadph to glyceraldehyde-3-phosphates. 6 cycles required for production of 1 hexose.

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