Biological Membranes, Fluid Mosaic Model, Membrane Proteins

3 Pages
73 Views
Unlock Document

Department
Biochemistry & Molecular Bio.
Course
BIOCHEM 524
Professor
David Gross
Semester
Spring

Description
Feb 28 Notes • central dogma of molecular biology o DNA– RNA– protein • protein compartmentalization is key level of cellular control o cellular control levels:  transcription  post-transcription  translation  post-translation  localization (within cell)  quality control • structure & properties of biological membranes o lipid bilayer  classes of membrane lipids  formation of micelles & bilayers  biological membrane dynamics o membrane proteins  classes of membrane proteins  structural features of membrane proteins  membrane protein dynamics o membranes as semi- & selectively permeable barriers  membrane permeability  membrane transport  membrane electrochemical potential • modified fluid mosaic model o lateral diffusion of membrane proteins can be restricted by interactions w/ cytosolic structures (cytoskeleton) • membranes are semi- & selectively permeable o hydrophobic molecules (O2, CO2, N2, steroids, hormones) pass through freely o small uncharged polar molecules (H2O, urea, glycerol) some pass freely through o large uncharged polar molecules (glucose, sucrose) size restricted passage, need assistance o ions (H+, Na+, HCO-, K+, Ca2+, Cl-, Mg2+) don’t pass through membrane w/o assistance • basis of membrane electrochemical potentials o this is a chemical concentration gradient o the elec
More Less

Related notes for BIOCHEM 524

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit