BIOLOGY 151 Lecture Notes - Lecture 6: S Phase, G1 Phase, G2 Phase
Document Summary
Phosphatases can turn off targets of protein kinase a. Gtpase converts gtp to gdp camp activation of pka. Pka is blocked by a regulatory subunit camp binds the regulatory subunit and releases active pka. Activated ras could bind to adenylyl cyclase, and prevent g alpha from binding. True; ras is one g protein and cannot activate adenylyl cyclase when it binds to adenylyl cyclase, while g alpha can bind and activate adenylyl. Activated mapk could activate g protein alpha gaps true; g protein alpha gaps would shut off the next step and the signal from the adrenaline receptor diminishes. Pka could activate ras gaps false; gaps shut g proteins off which would shut off the egf pathway. False; would not block the egf pathway it would activate the egf pathway. False; egf pathway effectively shuts down the adenylyl pathway. If the g protein alpha gap also targeted ras. True; gap targeting ras that turns ras off.
