MICROBIO 140P Lecture Notes - Lecture 11: Major Trauma, Chemical Substance, Antibody

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Lecture 11: ecology and emergence of disease. Epidemiological transmission periods: 1st neolithic revolution, sedentary communities, irrigation, domestication, 2nd 19th/20th century science and technology, pasteur, koch, Fleming, antibiotics: 3rd drug resistance, insecticide resistance, new pathogens. Underlying causes of emerging disease phenomena: artifacts of detection and naming, changes in human activity, domestication of animals, seeking new habitats, evolution and ecological change, climate, pathogenicity. Emerging diseases: resurgence or recurrence of old diseases (via mutation or exposure, diseases of animals that jump species and become new diseases of humans (zoonosis) Syndromes previously known but not ascribed to a particular cause. Identifying the causes of disease: a cause is a direct and necessary factor that results in disease state in affected individuals, pathogen (microbial agent, chemical substance, physical trauma. Lesions (or impaired functions: a region in an organ or tissue that has suffered damage through injury or disease, such as a wound, ulcer, abscess, tumor, etc.

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