MICROBIO 160 Lecture Notes - Lecture 25: Maraviroc, Peptide, Enfuvirtide

• School: UMASS-Amherst
• Department: Microbiology
• Course: MICROBIO 160
• Professor: Heather Reed

Document Summary

Check in 8 due monday today at noon. Exam 3: december 13th, 50 multiple choice. Mtct fell by 52% between 2001 and 2012. About 90% of these infections occurred in africa where aids revered decades of steady progress in child survival. Under no treatment mtct is between 15%-45%. Antiretroviral treatment (art) can reduce mtct to under 5% or better. Infected mothers now should receive lifelong art regardless of cd4+ cell count. Infants receive art based on breastfeeding or not for 6 weeks, then diagnosed and treated appropriately. 50% of mtct can be attributed to stigma associated with hiv related services. Infants infected with hiv through trauma of birth and breastfeeding (sometimes communal) Reduce viral load and increase t-cell count. Prolong life and improve quality of life. Suppress hiv levels (viral load) below the limit of detection (<50 copies hiv rna) or as low as possible for as long as possible. Optimize and extend the use of current therapy.