MICROBIO 160 Lecture Notes - Lecture 28: Progressor, Ex Vivo, Capsid

• School: UMASS-Amherst
• Department: Microbiology
• Course: MICROBIO 160
• Professor: Mitchell Walkowicz

Document Summary

Prediction vaccines will not be the way we beat this. Both patients had been infected for many years and had been on antiretroviral therapy that suppressed hiv replication but continued to have detectable virus prior to transplantation. History of the epidemic: preventive measures such as abstinence, faithfulness and condom use have reduced the spread of hiv infection but have not stopped it. There are no drugs that can cure hiv/aids, and drugs to treat the disease are expensive and not widely available in developing countries (1/3 of hiv positive in developing world getting treatment right now) Subunit vaccines - uses only the necessary parts of the virus to stimulate immunity, both safe and effective. Polio - 47 years for licensed vaccine in us. Preventive vaccine: prevent infection in people who are hiv negative: accounted for the bulk of early vaccine research. Researchers tried to encourage the immune system to produce antibodies that would block the virus from infecting cells.