Behavioral Neuroscience, Lecture on October 31 st
The study of the interactions between the nervous system and the endocrine
Interactions between the endocrine, immune and nervous system.
Neuroendocrine glands are ductless.
Releases hormones directly into the blood stream.
Release hormones at lower levels than the synapse.
Exocrine glands have ducts.
Secrete hormones such as dopamine
Important in metabolism and energy control
Secretes thyroxine and triiodothyronine
Growth hormone, oxytocin, etc.
Neurocrine = synaptic transmission.
Neuroendocrine nervous tissue,
Can be long-term effects
Hormones act on receptors,
Traditionally hormones are at lower concentrations compared to the
concentrations you would find in a synapse.
Hormones typically have a high affinity for their receptors.
Can act on receptors by traveling long distances.
Not all hormones are created equally!
Typically lipophilic (direct translation = likes fats),
Has implications – can pass through the membrane.
Bind to receptors in the cytoplasm or in the nucleus.
Can be hydropholic,
Acts on membrane receptors to initiate actions. Three main types of hormones, in terms of chemistry,
Amines (example, norepinephrine or dopamine).
Peptides/proteins (example, insulin or oxytocin).
Steroids (example, estradiol or testosterone).
MOSTLY derived from the amino acid tyrosine, produced by the thyroid.
Epinephrine, norepinephrine and dopamine are the putative tyrosine