EHS 385 Lecture Notes - Lecture 19: Cardiovascular Disease, Standard Deviation, Vascular Resistance

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3 purposes: transport o2/nutrients to tissues, remove co2 waste from tissues, regulate body temp. 2 adjustments of blood flow during exercise: increase cardiac output and redistribute blood flow from inactive organs to active muscle. Pulmonary: right side of heart, pumps deoxygenated blood to lungs via pulmonary arteries, returns oxygenated blood to left side of heart via pulmonary veins. Systemic: left side of heart, pumps oxygenated blood to body via arties, returns deoxygenated blood to right side of heart via veins. Deliver adequate amount of oxygen and remove wastes from body tissues. Heart wall: epicardium (outer layer), myocardium (middle layer composed of cardiac muscle fibers), endocardium (inner layer) Receives blood via coronary arteries, high demand for o2/nutrients. Myocardial infarction (mi): blockage in coronary blood flow results in cell damage, exercise training protects against heart damage during mi. Cardioprotective: reduces incidence/improves survival from heart attack. Reduces amount of myocardial damage from heart attack: improves antioxidant capacity, improved function atp-sensitive potassium channels.

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