BIOL 4004 Lecture Notes - Lecture 1: Lipid Bilayer, Glycerophospholipid, Integral Membrane Protein

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23 Dec 2015
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Mbc5 study guide chapter 10 (membrane structure) All living cells have a boundary called the plasma membrane that separates the cytoplasm from the external environment. Eukaryotic cells also have internal membranes that create organelles such as the cell nucleus. In this chapter, we will focus on structural aspects of membranes and membrane proteins. When exposed to water, certain types of lipids form a bilayer (figure 10-1). Membrane proteins may be embedded in the bilayer structure. In this section, we will consider structural features of lipids that cause them to form a bilayer, and we will examine the dynamic aspects of lipid bilayers and biological membranes. Phosphoglycerides, sphingolipids, and sterols are the major lipids in cell membranes. The most abundant membrane lipids are phospholipids, and the most abundant phospholipids are phosphoglycerides (figure 10-2). Phosphoglycerides are amphipathic because they have a polar head and two nonpolar tail regions.

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