CHEN 3701 Lecture 43: 2015_11_30 Lecture
9 Dec 2015
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Note from last lecture for [s]0 >> ks. Sum of all chemical reactions within a cell can be described in terms of. Catabolism: breakdown of complex molecules to simpler molecules. Anabolism: formation of complex molecules from simpler ones. Material balances and enzyme kinetics can effectively describe the system. Energy storage consider oxidation in glycolysis can couple this to atp generation (reverse 1st rxn) so what pushes the rxn eqbm is the concentrations and enzyme activities since they are now energy neutral. Oxidation & reduction pyruvate reduction to lactate reduction oxidation pyruvate lactate oxidation - loss of electrons reduction - gain of electrons. H atoms often carried by nicotinamide adenine dinucleotide (nadh) Nadph red = nadp+ this is the dominant one just like atp is dominant source of energy. Breaks down glucose to produce: atp for energy, nadh for reducing power, pyruvate as an intermediate for future metabolism. Preparatory phase - consumes 2 atp per glucose.
