Lecture 4282014.pdf

6 Pages
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Department
Chemistry
Course Code
CHEM 2332H
Professor
Christopher J.Douglas

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Description
Lecture 4282014Monday April 28 2014908 AMTodayMore on the michael RxnRobinson Annulation Tandem RxnProblemsMichael Rxn addition of carbon nucleophile to the betacarbon of an alpha beta unsaturated carbonyl system or similar electrophileGood Michael Nucleophilemalonic ester enolatesacetoacetatetype enolatesbetadiketone enolatesbetaketonitrile type Xamide ester ketonebasially all have good resonance stabilization Ochem Page 1
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