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Lecture 15

HMED 3075 Lecture 15: The History of the American Pharmaceutical Industry
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4 Pages
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Department
History of Medicine
Course Code
HMED 3075
Professor
Tobbell D

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HMED 3075 Lecture Notes on 11/9/16
Topic: The History of the American Pharmaceutical Indusrty
Reading: Buying Dad from a sperm bank
Pharmaceutical Companies in the late 19th century
Ethical Pharmaceutical firms
o Small family-run companies
Ex parke-davis and co (1866)
Manufactured, packaged, and sold drugs and other remedies under
trade/brand names
Fine chemical manufacturers
o Ex Pfizer(1849)
o Bulk manufactured chemicals
Patent medicine sellers
o Often high in alcohol content or containing morphine, cocaine, opium, radium,
or other dangerous ingredients
o Of little therapeutic value
o Sold openly to the public
o Available for almost any ailment and claimed to cure or prevent almost any
ailment
Pharmaceutical Firms before World War I
Physicians highly suspicious of patent medicine sellers and drug companies alike-
considered both unethical
Pharmaceutical firms worked to distinguish themselves from patent medicine sellers
o Did not patent drugs or advertise products to the public
o Marketed their products only to physicians
o Engaged in scientific research to develop new products
o Hired scientifically and medically trained personnel
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Description
HMED 3075 Lecture Notes on 11/9/16 Topic: The History of the American Pharmaceutical Indusrty Reading: Buying Dad from a sperm bank th Pharmaceutical Companies in the late 19 century • Ethical Pharmaceutical firms o Small family-run companies ▪ Ex parke-davis and co (1866) ▪ Manufactured, packaged, and sold drugs and other remedies under trade/brand names • Fine chemical manufacturers o Ex Pfizer(1849) o Bulk manufactured chemicals • Patent medicine sellers o Often high in alcohol content or containing morphine, cocaine, opium, radium, or other dangerous ingredients o Of little therapeutic value o Sold openly to the public o Available for almost any ailment and claimed to cure or prevent almost any ailment Pharmaceutical Firms before World War I • Physicians highly suspicious of patent medicine sellers and drug companies alike- considered both unethical • Pharmaceutical firms worked to distinguish themselves from patent medicine sellers o Did not patent drugs or advertise products to the public o Marketed their products only to physicians o Engaged in scientific research to develop new products o Hired scientifically and medically trained personnelPharmaceutical industry between WWI and WWII • WWI o US lost access to German chemicals and pharmaceuticals o American drug firms took over production in order to meet domestic demand • After WWI: o Development of industrial research laboratories o Securing of patents on innovations o Establishment of collaborative relationships between drug companies and academic researchers and clinicians ▪ Research grants, fellowships, consulting ▪ Innovations patented or licensed to firm, royalties to university Pharmaceutical Innovations before 1940: • Insulin: discovered in 1921 at U of Toronto and commercially developed in 1922 o Transformed juvenile diabetes from fatal disease to chronic disease to be managed • Sul
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