LAMP 4177 Lecture Notes - Lecture 2: Unpaired Electron, Cellular Respiration, Radiant Energy
4 Apr 2016
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For many agents the exact biochemistry cell injury in unknown. Intracellular systems vulnerable to cell injury: maintenance of cell membranes, aerobic respiration, synthesis of enzymatic &structural proteins, preservation of the integrity of the genetic apparatus (aka dna) 1: free radicals- molecules that have an unpaired electron in the outer orbit, produced by radiant energy or metabolism b. like to bind to lipids, proteins and dan. Necrosis: the sum of the morphologic changes that follow cell death in a living tissue or organ. Apoptosis: distinctive form of cell death resulting from activated enzymes that degrade the cell"s own nuclear dna and nuclear and cytoplasmic proteins. Where do we see apoptosis? tissues that lose hormone stimulation: cell death in tumors.
