Filter By
Filter Reset
Semester
Class Notes (1,031,116)
US (404,594)
UNE (31)

Class Notes at University of New England

GENE 500 Lecture Notes - Lecture 11: Sodium Chloride, Two-Dimensional Gel Electrophoresis, Polyacrylamide Gel Electrophoresis
Premium

Lecture 11 Purifying, Detecting Characterizing Proteins A protein must be puried to determine its structure and mechanism of action Molecules, including proteins, can be separated from other molecules based on differences...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 12: Chromogenic, Chemiluminescence, Electrophoresis
Premium

Genetics 500: Molecular Biology Introduction LECTURE 12 - Immunoblots Immunoblotting, also called Western blotting, combines the resolving power of gel electrophoresis with the specificity of antibodies. This multistep pro...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 13: Tandem Mass Spectrometry, Mass Spectrometry, Molecular Mass
Premium

Lecture 13 Molecular Mass Protein Sequencing Molecular mass can be determined by matrix- assisted laser desorptionionization timeof- flight (MALDI-TOF) mass spectrometry. Step 1: In a MALDI-TOF mass spectrometer, pulses of...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 6: Dissociation Constant
Premium

Lecture 6 Protein Design Common principle in previously listed types of function is ability to bind to things (other proteins, ions, other macromolecules....ligands) Binding often involves conformational changes Binding is...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 9: Circadian Rhythm, Proteasome, Intrinsic Activity
Premium

Lecture 9 Regulating Protein Function Alter steady state amount Alter rate of synthesis Alter rate of degradation Alter activity of protein Alter non-covalent, including allosteric, interactions Alter covalent modications ...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 10: Guanine Nucleotide Exchange Factor, Gtpase, Intrinsic Activity
Premium

Lecture 10 : Types of Regulation G-Protein Switches (Regulation) Large family of GTP binding and hydrolyzing proteins where a protein conformational change is caused by GTP binding GAP proteins control how long G protein r...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 7: Reaction Rate, Activation Energy, Macromolecule
Premium

Lecture 7 Basics of Enzymes Proteins that catalyze chemical reactionsthe making and breaking of covalent bondsare called enzymes, and the ligands of enzymes are called substrates. Another form of catalytic macromolecule in...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 8: Scaffold Protein, Cellular Compartment, Metabolic Pathway
Premium

Lecture 8 - Antibodies Protein Complexes Antibodies stabilize the ground state Enzymes stabilize the transition state Some transition states are stable enough that they can be trapped and used as antigens The antibodies p...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 2: Coiled Coil, Leucine Zipper, Structural Motif
Premium

Lecture 2 - Structure Motifs A particular combination of two or more secondary structures that form a distinct three- dimensional structure is called a structural motif when it appears in multiple proteins Structural motif...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 5: Energy Landscape, Protein Folding, Ribonuclease
Premium

LECTURE 5 Correcting Misfolded Proteins Although a small protein like ribonuclease can fold spontaneously, even it is slow by biological standards In the cell, protein folding is assisted by chaperones and chaperonins Chap...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 1: Conformational Change, Covalent Bond, Proline
Premium

Lecture 1 - Protein Structure These functions summarize the main functions of the proteins Proteins develop many of these diverse functions through exploiting a few simple activities: Most fundamentally, proteins bindto on...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 4: Energy Landscape, Protein Folding, Ribonuclease
Premium

Lecture 4 - Number of Proteins Correcting Misfolded Proteins Although a small protein like ribonuclease can fold spontaneously, even it is slow by biological standards In the cell, protein folding is assisted by chaperones...

Genetics
GENE 500
Lawrence Grossman
GENE 500 Lecture Notes - Lecture 3: Alternative Splicing, Protein Folding, Intron
Premium

Lecture 3 Protein Evolution Number of Proteins Molecular chaperones, which bind to a short segment of a protein substrate and stabilize unfolded or partly folded proteins, thereby preventing these proteins from aggregating...

Genetics
GENE 500
Lawrence Grossman
AFM 101 Lecture Notes - Lecture 5: Royal Meteorological Society, Polar Vortex, Meteorology

Winter 2016/17 Tentative weather prospects 27/06/2016 UPDATE 15/09/16 now online UK winter 2016/17 weather forecast indicators It's a long way off but are there any early pointers to how winter 2016/17 may turn ou...

AFM
AFM 101
Tennenhouse

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit