BIOS 111 Lecture 2: BIOS 111 Lecture 2 (1/11/17)

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6 Feb 2017
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BIOS 111 Lecture 2 (1/11/17)
Advantages of Bacteria:
A bacteria is only one micron in size so you can get lots
About 109bacteria per mL
Bacteria grow very rapidly
Generation time of 20-30 minutes
Bacteria have one copy of DNA (chaploid), so it’s very easy to get mutants.
Bacteria are single cell organisms
There are ~4,000 genes in an entire genome
We can get the complete DNA sequence within days
We can define how to grow bacteria by controlling temperature, atmospheric pressure,
saline, water, etc.
This is what George Beadle did to detect mutants.
Unity of biochemistry says bacteria are similar in biochemistry to higher organisms.
They use the same metabolic pathways, amino acids, genetic code, ATP, and
vitamins.
Yeast are the model system for eukaryotes.
Aging, cancer, obesity, etc.
The air is full of microbes, so microbial infections can kill patients in surgery.
Fixed by antiseptics
Childbirth fever was caused because bacteria was spread from autopsies → medical
students → mother giving birth
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