BIOL 203 Lecture Notes - Lecture 4: Gamete, Mitochondrion, Polyploid
Document Summary
Genetic drift, gene flow, mutation, and the science of variance. Ss: no anemia, healthy but no resistance to malaria. Ss: severe anemia, resistance to malaria, commonly results in death in early childhood. But the observed frequency of ss is 52%, meaning that this population is not in hardy-weinberg equilibrium. Hardy-weinberg assumptions: no natural selection (ns, no random allele frequency changes (genetic drift, no movement of new alleles into or out of the population (pop) (gene flow, no mutations, random mating. Non random vs random evolution: ns is not random, rest of the processes of evolution are random. Sampling: taking few things form a larger group. Can lead to extinction or fixation of alleles by chance. Can occur when new pops are established in a new area; loss of genetic diversity. Allele frequencies may greatly vary from original pop. Samples of a small population from a large group limited gene sampling.