BIOC 3110 Lecture Notes - Lecture 28: Methylene Group, Aspirin, Acetaldehyde
3 Nov 2016
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Fatty acid synthesis occurs when you have lots of energy, lots of carbon, which says there is spare to make fatty acids, to use to make membranes. What are the building blocks for fatty acid synthesis: nadph (reducing power, acetyl coa. Where do the building blocks come from: nadph comes from the pentose phosphate pathway and the transport of acetyl coa into cytoplasm, acetyl coa comes from citrate/glycolysis. Where does fatty acid synthesis occur: occurs in the cytoplasm. What are the three basic stages for fatty acid synthesis: 1. Move acetyl coa from mitochondria into the cytosol. Acetyl coa is condensed with oxaloacetate to form citrate, which can cross the membrane into the cytoplasm. Once in cytoplasm lyase and atp cleaves citrate to regenerate the acetyl coa and oxaloacetate (4c) Oxaloacetate in cytoplasm can either be used here to make amino acid, or move back into mitochondria.
