BIOC 3110 Lecture Notes - Lecture 37: Transfer Rna, Arginine, Transcription Factor Ii D
Document Summary
Tfiih phosphorylates core polymerase, which allows rna. General transcription factors (needed to get any rna synthesis) main types are: Tfiid-critical component for assembling rnap ii: contains a protein within the unit called tbp, which binds to the tata box, and brings the. Tfiih-protein unit apart of the intitiation complex, that serves as a helicase (unwinding the dna) and a kinase activity (which phosphorylates the pol ii ctd, which gives the rnap ii a push to begin moving down and synthesizing) Mediator-set of proteins that bind both transcription factor and rnap ii; brings together activators and rnap complex and makes them work better through promoting hyperphosphorylation of rnap ii. How does an enhancer differ from a promoter: promoter has essential elements needed for transcription that varies from rnaps. Rnap1: promoter elements close to transcription state; sequences that bind to parts of rnap1 that initiates transcription. Rnap ii: core binding sequences make up promoter that transcription factors recognize.