HHP 3500 Lecture Notes - Lecture 41: Juxtaglomerular Apparatus, Vasodilation, Blood Pressure

• School: University of Iowa
• Department: Health and Human Physiology
• Course: HHP 3500
• Professor: Peterson Clayton

Document Summary

Created by regulation of urine excretion mainly, also from sweat, feces, and insensible loss. For controlling both of these tings, the major control point is regulation of renal excretion; both na and h2o are nearly fully reabsorbed. How do we control these: increase in gfr rate, leads to more excretion. Decreased osmotic force in glomeruli (from decreased. Increased blood volume + increase in map, causing increase in glomerular pressure. Urine concentration occurs in medullary collecting duct(loops of henle) Typical ect osmolarity = 300 mosm; this allows us to concentrate it to 1400mosm, which allows us to absorb more. Active pumping of nacl occurs in the ascending limb. This causes us to pump sodium into interstitum, but water cannot follow because impermeable. Water then flows out of the descending limb, but sodium cannot follow, so this concentrates fluid in descending limb. So now both interstitum and descending limp are concentrated.