HHP 3300 Lecture Notes - Lecture 3: Parathyroid Gland, Intellectual Disability, Paracrine Signalling

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Hormone concentration can also induce increases in receptors (e. g. , beard growth occurs later in puberty) Other growth-promoting factors and hormones: growth-promoting factors are secreted by many tissues, or by select cell types, and they have systemic or highly localized effects. Implications for growth, aging, recovery from injury, burn, surgery, atherosclerosis, cancer, and much more. Important growth factors: fibroblast growth factor, epidermal growth factor, nerve growth factor, platelet-derived growth factor, vascular endothelial growth factor, tumor necrosis factor, and insulinlike growth factor (igf-i and igf-ii). Can act in a paracrine or an autocrine fashion, and may serve as second messengers for some of the endocrine hormones (e. g. , igf-i and. Hormone actions: morphogenesis regulate the physical growth and maturation of the individual (rate of growth, maturation of gonads and secondary sex characteristics. Some growth occurs in absence of growth-promoting hormones, but these hormones are necessary for full expression of the intrinsic growth pattern of body tissues.

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