MICR 3164 Lecture Notes - Lecture 1: Scanning Electron Microscope, Gram Staining, Transmission Electron Microscopy

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Characteristics of eukaryotes vs. prokaryotes: eukaryotes o possess a nucleus o ribosomes are 80s o complex cellular structure containing additional organelles, examples o fungi o parasites. Microbes harming humans: the majority of microorganisms that associate with humans cause no harm, pathogens: microbes that cause disease, the world health organization (who) estimates that there are 10 billion new infections caused every year by microbes. Increasing number of emerging diseases (sars, aids, hepatitis c, viral encephalitis: other diseases previously not linked to microorganisms now are (gastric ulcers, certain cancers, schizophrenia, multiple sclerosis, obsessive compulsive disease, coronary artery disease) The discovery of pathogens and the germ theory of disease: louis pasteur o pasteurization o the germ theory of disease, robert koch o koch"s postulates-verified the germ theory. 1. 4 pasteur"s swan neck flask experiment that disproved spontaneous generation in 1861. Discovery of microscopic life in 1673 (first microscope) Koch"s postulates: evidence required to establish etiologic relationship between microorganism and disease.

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