BIOL 540 Lecture Notes - Lecture 40: Fatty Alcohol, Acyltransferase, Ethanolamine
Document Summary
Lipid remodeling acyltransferase reactions ultimately influence acyl distribution acyl composition is not absolute phospholipase a and phospholipase az hydrolyze specific acyl groups from exact locations can be reacylated it with another fatty acid these positions. G acyltransferase taking off specific fatty acids and replacing transaculation mixing acyl groups between lipid species plasmalogen synthesis synthesized in the peroxisome found mostly in heart coupling tissues because they are more stable utilizes glycolytic intermediate dhap. 1 dhap acyltransferase acylates the sni position of dhap makes acyl dhap a for. Sphingolipids present in nearly all tissues abundant in white matter nervous tissues sphingolipids are synthesized from sphingosine which is derived from serine and palmitoyt coa. 1 serine palmituyltransferase catalyze the condensation of serine and palmitoyl coa to yield 3 ketodihydrosphingosine. Oz and gash acylate sn"s position nitrogen is part of the structure. 2 3 ketodihydrosphringosine is reduced using nadph to form sphinganine lor dihydrosphingosine.
