NURS 464 Lecture Notes - Lecture 10: Sickle-Cell Disease, Secondary Sex Characteristic, Delayed Puberty
Document Summary
Endocrine system is what determines male or female fetus. Growth: plot on growth chart. genitalia, inappropriate for age. Body odor: unusual smells- sweet, eyes, moon face musty, sweaty, Sickle cell disease can cause an infarct in the pituitary. Diagnosis: annual growth < 5cm of growth, marked flattening of growth curve, height < 5th percentile. Gh < 10 on 2 separate occasions = malfunction. Treatment: administer gh at bedtime 6-7 times per week until growth plates close. Nursing: if at risk, send to endocrinologist. Insulin, catapres, duraclon, (clonidine hydrochloride) all stimulate the release of growth hormone during the day. Autoimmune disease where beta cells within the islet of langerhan"s are destroyed. No insulin is produced bc no beta cells. Excess glucose bc no insulin to get rid of. Catabolism (breakdown of fat and proteins) produces ketones in the urine. Peak age of dx is 5-7 years, and during puberty. Usually not dx until come into ed with ketoacidosis.
