BIOL 522 Lecture Notes - Lecture 4: Introgression, Scale-Invariant Feature Transform
Document Summary
Different groups and it"s informative of how hominids interact: gather source of genomic data/ fossils, generate and sift through genomic data, review neanderthal phylogenies tree, apply data to context of introgression. Neanderthals are different in different regions of the world. Dna degradation is predictable, so they limited analysis to fragments with c & t end substitutions. Look at conserved regions because they align better. Mtdna passed down from maternal side, more conserved. Fig 2c phylogenies tree, age and location of different samples, among late neanderthal samples there"s lots of genetic similarities. Authors show that despite geographic separations, heavy gene flow from samples in european context into russian geographic context, so there"s not that many samples. D statistics, taking test subject (specific neanderthal) and new samples that they got, compare 2 groups.
